Miglitol (Rx)

Miglitol Brand name: Glyset

Dea Class: Rx (Prescription drug)

Drug Class: Antidiabetic, Alpha-Glucosidase Inhibitors

Dosage form: Tablet 25mg, 50mg, 100mg

In this Post

What is Miglitol and how does it work?

Miglitol is oral alpha-glucosidase inhibitor; in contrast to acarbose, miglitol is systemically absorbed before acting in GI tract

It is used for the treatment of type 2 diabetes mellitus

Agents in this class have only modest effects on A1C (i.e., mean 0.3% to 0.7% reduction)


What are Miglitol uses?

It is used for the treatment of type 2 diabetes mellitus as an adjunct to diet and exercise.


How should I take Miglitol?

Miglitol comes as a tablet to take by mouth. It is usually taken three times a day with the first bite of a meal. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take it exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.


Side Effects

The common side effects don’t need medical attention and will disappear as your body adjusts to the dosage. But if you are facing any serious or rare side effects, then immediately seek medical attention.

  • Flatulence (42%)
  • Diarrhea (29%)
  • Abdominal pain (12%)
  • Rash (4.3%)
  • Low serum iron

What Are Warnings and Precautions for Miglitol?

Warnings

Concurrent use with sulfonylureas may result in hypoglycemia; treat hypoglycemia with oral glucose, not sucrose

Before taking Cautions

Hypersensitivity

Diabetic ketoacidosis, inflammatory bowel disease, colonic ulceration, partial intestinal obstruction

Disorders of GI digestion or absorption

Conditions that may deteriorate due to increased GI gas

Severe renal impairment

Pregnancy and Lactation

Pregnancy

  • Pregnancy Category: B

Lactation

  • Enters slightly into breast milk; nor recommended

Dosages?

Tablet 25mg, 50mg, 100mg

Adults

300 mg/day PO.

Geriatric

300 mg/day PO.

Adolescents

Safety and efficacy have not been established.

Children


Miglitol brand name

Brand name : Glyset

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